Sleep and circadian rhythms: do sleep centers talk back to the clock?
نویسندگان
چکیده
منابع مشابه
Circadian rhythms, sleep, and metabolism.
The discovery of the genetic basis for circadian rhythms has expanded our knowledge of the temporal organization of behavior and physiology. The observations that the circadian gene network is present in most living organisms from eubacteria to humans, that most cells and tissues express autonomous clocks, and that disruption of clock genes results in metabolic dysregulation have revealed inter...
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Genetic analyses of circadian rhythm sleep disorders (CRSD), such as familial advanced sleep phase syndrome (ASPS) and delayed sleep phase syndrome (DSPS), and morningness-eveningness revealed the relationship between variations in clock genes and diurnal change in human behaviors. Variations such as T3111C in the Clock gene are reportedly associated with morningness-eveningness. Two of the ped...
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The temporal interplay between genetic and epigenetic mechanisms determines behavioral, physiological and molecular phenotypes across the organism. The understanding of how genetic sequences translate in complex phenotypes is a major challenge in current functional genomics. This difficulty is due to the fact that modules of genes co-express [2] and a particular phenotype results from the preci...
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The 24-hour (h) light–dark (LD) cycle is a fundamental characteristic of Earth’s environment and so its powerful influence on the behaviour and physiology of animals and humans that evolved on this planet is not surprising. In addition to influencing the perception of visual images, light coordinates the temporal rhythms of physiology and behaviour by sending signals to structures in the brain ...
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ژورنال
عنوان ژورنال: Nature Neuroscience
سال: 2003
ISSN: 1097-6256,1546-1726
DOI: 10.1038/nn1003-1005